Live.js works in Firefox, Chrome, Safari, Opera and IE6+ until proven otherwise. Live.js is independent of the development framework or language you use, whether it be Ruby, Handcraft, Python, Django, NET, Java, Php, Drupal, Joomla or what-have-you.
Live.js was written by Martin Kool as the next step in Handcraft’s design in the browser strategy. But similar to when we open sourced Backfire (which allows you to save CSS changes made with Firebug) it seemed natural to once again share the code.
PS: Make sure you protect the page where you make the changes 😉